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Study finds higher risk of immune issues in children of HIV-positive mothers
Overview
In a study published in the journal Nature Communications, researchers from Queen Mary University of London have found that children of women with HIV infection have an increased risk of immune abnormalities following exposure to maternal HIV viremia, immune dysfunction, and co-infections during pregnancy.
Moving forward, further research is warranted to elucidate the underlying mechanisms driving sex-specific differences in mortality and immune development in HIV-exposed infants. By gaining a deeper understanding of these complex interactions, researchers aim to inform targeted interventions and improve long-term health outcomes for this vulnerable population.
Reference: Evans, C., et al. (2024). Inflammation and cytomegalovirus viremia during pregnancy drive sex-differentiated differences in mortality and immune development in HIV-exposed infants. Nature Communications. doi.org/10.1038/s41467-023-44166-2.